Title: Genetic Toxicity of Alginate-Derived Oligosaccharide on Vicia Faba Root Tip Cells
Abstract: The effects of different concentrations of alginate-derived oligosaccharide(ADO) on Vicia faba root tip cells were studied.Micronucleus assay and chromosomal aberration assay were used to determine the mitotic index,the micronucleus rate and chromosomal aberration rate of Vivia faba root tip cells induced by arsenic trioxide under different concentrations of ADO.The result showed that ADO could effectively inhibit the micronucleus rate.During concentration of 10~0.625 g/L,the number of micronucleus of Vivia faba root tip cells were reduced with decrease concentration of ADO,but it was increased when concentration of ADO was lower than 0.625 g/L.The mitotic index was increased,while chromosomal aberration rate were lowered under all concentration of ADO.Turkey test showed all chromosomal aberration rate were significantly different from the control(p0.05).So,ADO has an obvious effect on restraining chromosomal aberration and increasing division of cell of Vivia faba root tip.
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
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