Title: Synthesis and Characterization of 1-Methyl-4,5-dinitroimidazole
Abstract: Taking imidazole as primary substance,1-methyl-4,5-dinitroimidazole was synthesized in DMF by reaction of methyl suifate((CH3)2SO4) with 4,5-dinitroimidazole obtained from nitration. Its structure was characterized by IR,elemental analysis,MS and 1H NMR. The nitration mechanism of 4,5-dinitroimidazole was analyzed. Results show that the yield of 1-methyl-4,5-dinitroimidazole is 62%,and its melting point is 77 ℃. The optimum parameters are obtained:reaction temperature is 45-50 ℃,and reaction time is 4 h,the molar ratio of 4,5-dinitroimidazole to (CH3)2SO4 is 1:6. The pH value of 4,5-dinitroimidazole (0.63 mol·L-1 acetone solution) is raised from 3.74 to 6.77 of 1-methyl-4,5-dinitroimidazole (0.63 mol·L-1 acetone solution).
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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