Title: Distribution of hepatitis B virus genotypes in Northern of Guangxi
Abstract: Objective To understand the distribution of hepatitis B virus genotypes in GuiLin,Northern Guangxi.Methods The nested polymerase chain reaction (nPCR) was used for amplification of HBV DNA in sera of 41 asymptomatic carriers(ASC) from GuiLin. The genotypes of the positive were determined by direct sequencing.Results Nineteen of them were positive for HBV DNA. Positive rate was 46.34%(19/41).15 cases'genotype was genotype B of HBV, counting for 78.9%(15/19). Four cases' was genotype C of HBV, counting for 21.1%(4/19). No other genotypes(such as genotype E,F,G,H of HBV) were found. The HBeAg positive rate was higher in the carriers with genotype C of HBV than in that with genotype B of HBV (P0.05).Conclusions HBV genotypes in GuiLin,Northern Guangxi is genotype B and C of HBV. The major genotype is genotype B of HBV in GuiLin,Northern Guangxi.
Publication Year: 2003
Publication Date: 2003-01-01
Language: en
Type: article
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