Title: The Expression of E2F-1 Gene in Lung Cancer
Abstract: Objective: To investigate the expression of E2F-1 in lung cancer.Methods: The expression of E2F-1 was detected at their protein level by Immunohistochemistry S-P method in 60 specimens of lung cancer and 20 specimens of normal lung tissue.Results: The positive expression of E2F-1 was 91.7%,which was significantly higher than 10% in normal lung tissues,and there was a signifi-cant difference between the two(P0.05);there was no relation between the expression of E2F-1 and the characteristics of lung cancer,i.e sex,age,tumor pathological type,differentiation,lymph node metastasis(P0.05).Conclusion: The expression of E2F-1 may play an important role in the occurrence of Lung cancer,and can be used to gene diagnosis.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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