Title: Expression of Epidermal Growth Factor and Epidermal Growth Factor-Receptor and its Significance in Colorectal Cancer
Abstract: Objective To investigate the expression of epidermal growth factor(EGF)and epidermal growth factor-receptor(EGF-R)and its significance in colorectal cancer.Methods The expression of EGF and EGF-Rwas detected by SP immunohistochemical method in 10 cases of normal colorectal membrane and 64 cases of colorectal cancer.Results The expression of EGF and EGF-R were both negative in normal colorectal membrane,but were 51% and 66%,respectively,in colorectal cancer,showing a significant difference between the two groups.There was a positive correlation between the expression of EGF and EGF-R in colorectal cancer.Conclusion The EGF and EGF-R play an important role in the carcinogenesis and development of colorectal cancer.
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot