Title: Echocardiographic assessment of left ventricular structure and cardiac function in children with hypertension
Abstract: Objectives To evaluate the changes of cardiac function and structural parameters in children and adolescents with essential hypertension(EH),and to assess the adverse effects on target organ.Methods Cardiac function and structural parameters were measured in 47 EH children with echocardiography(EH group)and 62 healthy children were studied as control.Results Compared with control group,interventricular septum thickness in end diastole(IVST.D),posterior left ventricular wall thickness in end diastole(LVPWT.D),left ventricular diameter in end diastole(LVED.D),left ventricular diameter in end systole(LVES.D),left ventricular mass(LVM),left ventricular mass index(LVMI)were all significantly higher(P0.01);while ejection fraction(EF),left ventricular fractional shortening(FS)were significantly lower in the EH group(P 0.05).Descending E peak in end diastole was lower in the EH group,but with no statistical significance(P0.05).In the EH group,peak in end diastole was enhanced(P0.05),and E/A ratio was significantly lower(P0.01).Some of the patients were found to develop left ventricular hypertrophy.Conclusions In children with hypertension,the heart as a target organ had developed some degree of functional and structural changes(remodeling).
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
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