Title: The Relationship between Cardiac Troponin I and Chronic Heart Failure
Abstract: [Objective]To explore the relationship between cardiac troponinⅠ(cTnI)and chronic heart failure(CHF),and to study the clinical significance of cTnI on the prognosis of CHF.[Methods]Serum level of cTnI,serum activities of creatine kinase(CK),creatine kinase-MB(CK-MB),and ejection fraction(EF)monitored for heart function were measured in 108 patients with CHF and 38 healthy cases(control group).[Results] Serum level of cTnI was higher in patients with CHF than that in the control group significantly(P0.05).CK and CK-MB in the cTnI increased group were both higher than those in the cTnI normal group(P0.05),and EF in the cTnI increased group was lower than that in the cTnI normal group significantly(P0.05).[Conclusion]Serum level of cTnI correlated with cardiac function in the patients with chronic heart failure.So the serum cTnI with the better sensitivity and specificity will help to evaluate the severity,cardiac function and prognosis in patients with heart failure,which can be used as a prognosis predicting indicator for them.
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
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