Title: Quantitative assessment of regional left ventricular contractile function in dogs during acute ischemia reperfusion using strain rate imaging
Abstract:Objective To investigate the feasibility of quantitative evaluation for regional left ventricular contractile function during acute ischemia reperfusion (AIR) using strain rate imaging (SRI) echocardi...Objective To investigate the feasibility of quantitative evaluation for regional left ventricular contractile function during acute ischemia reperfusion (AIR) using strain rate imaging (SRI) echocardiography. Methods Fourteen anaesthesia opened-chest dogs were scanned before, at 30 min after left anterior descending coronary artery (LAD) ligation, subsequently reperfused for 30 min, 60 min, 120 min. 3 complete cardiac cycles were stored in cine-loop format of tissue velocity imagine. Off-line left ventricular regional strain rate along long axis using digital workstation were obtained and analyzed the features of strain rate. Left ejection fraction (LVEF), end-diastolic volume (EDV) and end-systolic volume (ESV) were obtained by Simpson biplane method. Results AIR models of 12 dogs were successfully established from 14 dogs. The peak strain rate (SR_peak) in ischemia segment was decreased obviously (P0.05), and postsystolic compression (PSC) was found in ischemia segment. SR_peak was decreased seriously during reperfusion 30 min. SR_peak increased slightly after reperfusion 60 min and 120 min, but still decreased than before ligation. There was no significant difference between before and after LAD ligation at LVEF, EDV, ESV (P0.05). Conclusion Regional wall motion abnormalities can be evaluated quantitatively and synchronously with high sensitivity by strain rate which has potential value in early diagnosis of regional myocardial ischemia and reperfusion.Read More
Publication Year: 2007
Publication Date: 2007-01-01
Language: en
Type: article
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