Title: Effects of tongxinluo capsule on C-reactive protein and thromboxan B2 in patients with acute coronary syndrome companied with aspirin resistance
Abstract: Objective To investigate the effects of tongxinluo capsule on platelet aggregation rate and C-reactive protein(CRP) and thromboxan B2(TXB2) in patients with acute coronary syndrom(ACS)who had aspirin resistance(AR).Methods A total of 70 ACS patients who had AR were recruited.They were randomly assigned into conventional therapy group,tongxinluo group,clopidogrel group.platelet aggregation rate and CRP and TXB2 levels were detected before and after 1-month treatment.Results Tongxinluo and clopidogrel could both make platelet aggregation rate,CRP and TXB2 decrease in ACS with AR patients.The levels of platelet aggregation rate,CRP and TXB2 had statistical significance before and after treatment(P0.05,0.01).Conclusions Tongxinluo capsule has antiplatelet aggregation and anti-inflammatory effect in ACS patients with AR,and can improve AR in ACS patients in a certain degree.
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
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Cited By Count: 3
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