Title: Analysis of Syphilis Positive Results by Serological Detection among Patients with Cardiovascular Disease
Abstract: Objective To analyze the distribution of syphilis positive patients by serological detection among patients with cardiovascular disease,therefore to provide experimental evidence for the bio-security needed in the diagnosis,surgical intervention and medical intervention therapy of cardiovascular diseases.Methods Using Treponema pallidum particle agglutination test(TPPA test) and rapid plasma regain test(RPR test),we measured 255 patients with cardiovascular disease admitted to our hospital from January 2008 to May 2009.First,we inspected all samples with TPPA test,then re-examined TPPA-positive samples with RPR test.And,we randomly collected 200 cases of TPPA-Negative samples as the control group.Then,we analyzed the gender and age composition of syphilis-positive patients and the relationship with cardiovascular disease.Results In 255 TPPA test positive patients,84 patients were RPR test positive and 171 were negative.Male in RPR test positive patients were significantly more than female(X2=5.762,P0.05).RPR positive rate in five age groups had no statistical significance,however,patients older than 65 years had higher RPR positive rate(X2=8.607,P0.01).TPPA test positive patients had higher prevalence of aorta diseases(X2=8.392,P0.01;dissection of aorta vs.control:X2=4.435,P0.05,aortic valvular disease vs.control:X2=5.162,P0.05) and heart failure(X2=4.004,P0.05) than the control group(n=200).Conclusions In the RPR test positive inpatients of our hospital,male were significantly more than female and most patients were elderly people.Patients older than 65 years had significantly higher RPR positive rate,which might involve biological false positive.In TPPA positive patients,the prevalence of aorta diseases and heart failure were significantly higher than the control group,which might be induced by syphilis.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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