Title: Serological detection by combination of TRUST with TPPA and IgM antibody for syphilis patients with latent blood-transmitted risk.
Abstract: Objective To select serological screening indicators for syphilis patients with latent blood-transmitted risk. Methods A retrospective study on the TRUST and TPPA combination detection method was conducted between patients at latent blood-transmitted risk and outpatients in our hospital from,1 June,2006 to 31 December,2009. The percent of TRUST-/TPPA+in patients with latent blood-transmitted risk were analyzed in different years. Tp-IgM antibodies were detected in 118 cases of TRUST-/TPPA+patients at latent blood-transmitted risk. Results Syphilis antibody positive rate (26.69%) of outpatients was significantly higher than patients with latent blood-trans-mitted risk (8.62%).The rate of TRUST-/TPPA+in the syphilis-positive patients were 7.50% and 3.12%. The percent of TRUST-/TPPA+in patients with latent blood-transmitted risk is growing steadily year after year. 13 and 10 IgM antibody positive specimens were seeked out of the 118 latent blood-transmitted risk TRUST-/TPPA+sera by TPPA and FTA-ABS methods. Conclusions Serological screening for infectious syphilis should at least cover specific antibody tests, such as the TPPA; TP-IgM test would help determine contagiousness.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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