Title: Studies on the AChE Kinetics in Beijing Houseflies (Musca domestica L.)
Abstract: Characteristics of the AChEs of various houseflies populations (Beijing field population, susceptible strain and Propoxur (Arprocarb) resistance population) were investigated in 1990. The result shows that Km values and Vmax of AChEs were sigin-ficantly different among these flies. The extreme disparity were up to 4-fold, the value of Vmax close to 8-fold. The values of the biomolecular rate constant (Ki) of Trichlorphen to AChEs for the susceptible strain (SA) and the Beijing Xuanwu population were 7.41 × 104(L/mol ++ min-1) and 5.13 × 102(L/mol · min-1) respectively, so the value of Ki of AChE in the susceptible stain was 144 times more than that of Beijing Xuanwu. The Ki values of AChEs in Beijing Chongwen, Miyun, Huilongguan populations were 11.8-37.8 times less than the susceptible strain. This shows that the sensitivity of the Beijing population AChE's to Trichlorphen has decreased. The Kd value of AChEs in the Xuanwu population was 2890 times as much as the susceptible strain. The other populations were 50 times higher than the susceptible strain, but the phosphorylated rate constants (k2) were not much different among these flies. This seems to be attributed to an altered form of AChEs that have been produced in Beijing flies.
Publication Year: 1991
Publication Date: 1991-01-01
Language: en
Type: article
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