Title: Clinicopathological Features of 15 Cases with Intraductal Papillary Carcinoma of Breast
Abstract: Objective: To study clinicopathological features, diagnosis and differential diagnosis of intraductal papillary carcinoma of breast. Methods: The features of clinicopathology, histopathological morphology and immunohistochemistry of 15 cases of breast intraductal papillary carcinoma were analyzed with the review of literature. Results: All 15 cases showed papillary structure under low-power microscopy. The papillary was covered with monolayer or multilayer glandular epithelium which was perpendicular to the axis of palliary and showed variable heteromorphism. Immunostaining of SMA and p63 showed that myoepithelium was absent or discontinuous. The cancerous epithelium showed no or little expression of CK 5/6. Conclusion: Intraductal papillary carcinoma of breast is a rare and low grade malignante tumor with favorable prognosis. Immunostaining of SMA, p63 and CK 5/6 is helpful for correct diagnosis. The main differential diagnosis is intraductal papillary adenoma.
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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