Title: ANALYSIS OF DRUG-RESISTANCE ON 3653 SAMPLE OF TUBERCULOSIS PATIENTS
Abstract: [Objective] To summarize current situation of mycobacterium tuberculosis drug resistance in Changsha Central Hospital.[Methods] 3 653 sample of tuberculosis patients were performed drug resistance in the past 7 years.[Results] Rate of total drug resistance was 39.3%,rate of total multidrug resistance was 10.2%,rate of initial drug resistance was 37.5%,rate of initial multidrug resistance was 6.8%,rate of acquired drug resistance was 47.5%,and rate of acquired multidrug resistance was 25.3%.The sequence of single drug resistance from the higher to lower was INH(23.2%),SM(18.5%),RFP(15.9%),EMB(15.1%),TH1321(13.9%),PZA(11.5%),PAS(8.3%),OFX(6.5%),KM(6.2%) and LFX(2.2%),respectively.[Conclusion] Higher rate drug resistance and the trend of the first-line drugs resistance is the characteristic of mycobacterium tuberculosis in Changsha Central Hospital.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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