Title: Comparison of human Day 3 embryo cryopreservation by slow freezing or vitrification
Abstract: Objective: To compare the efficacy of vitrification and slow freezing for the cryopreservation of human Day 3 embryos.Methods:In the in vitro fertilization-embryo transfer cycles,supernumerary Day 3 embryos were cryopreserved by vitrification or slow freezing methods.After warming;the survival rate,clinical pregnant rates and implantation rates were compared between the two groups.Results: In 78 vitrified embryo thaw cycles,228 vitrified embryos were thawed,and 210(92.11%) of them survived,172(81.90%) embryos with 100% blastomere survival.77 women were transferred,and32(41.56%) of them got clinically pregnant.As to slow freezing method,in 157 embryo thaw cycles,702 embryos were thawed,405(57.69%)of them survived,207(51.11%) embryos with 100% blastomere survival.148 women were transferred,and58(39.19%)of them got clinically pregnant.The embryo survival rate,embryos with 100% blastomere survival were higher in vitrification group than those in slow freezing group(P0.05).Conclusion: In contrast to slow freezing,vitrification provides a higher survival rate.Vitrification is a more efficient method for cryopreservation of human Day 3 embryos.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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