Title: Analysis of 385 strains of Gram-negative bacilli in intensive care units
Abstract: Objective To investigate the specimen source,the distribution and commonly used antibiotic-resistant conditions of Gram-negative bacilli from intensive care units(ICU).Methods A retrospective study of 385 strains of Gram-negative bacilli from ICU was performed.Results Among the 385 strains,79.0% were from sputum specimen.Nonzymophytes accounted for 61.0% of isolates.A.baumannii had the highest isolated rate(27.0%).Except imipenem and piperacillin/tazobactam in which the resistance rates were 5.8% and 48.1% respectively,most antibiotics resistance rates among A.baumannii isolates exceeded 80%.The third generation cephalosporins resistance rates among P.aeruginosa isolates ranged from 43.2% to 97.9%.P.aeruginosa resistance to imipenem and amikacin was 42.1% and 15.8% respectively.The resistance rates of Enterobacteriaceae to many kinds of antibiotics exceeded 40% and E.cloacae was more remarkable.Imipenem marked a good antimicrobial action.The positive rates of ESBLs in E.coli and K.pneumoniae were 53.2% and 55.6% respectively.Conclusions Nonzymophytes has become the most common pathogens.For the high level resistance of the Gram-negative bacilli to commonly used antibiotics,it is very important to rationally choose the antibiotics.
Publication Year: 2007
Publication Date: 2007-01-01
Language: en
Type: article
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