Title: Effect of rosiglitazone on blood glucose and blood pressure in type 2 diabetic patients combined with hypertension
Abstract: OBJECTIVE To explore the effect of rosiglitazone on type 2 diabetic patients combined with hypertension. METHODS The 90 type 2 diabetic patients combined with hypertension were treated with rosiglitazone (4-8 mg·d-1 ) for 12 weeks on the basis of former hypotensive drug administration,alimentary control and exercise.Blood pressure,Ins and HbA1c were measured before and after treatment with rosiglitazone.RESULTS After 12 weeks of treatment, SBP and DBP were lowered significantly (P0.01).The levels of FPG,PPG,FINS and PINS changed significantly compared with those before treatment(P0.05),there was no significant change in patients’ weight(P0.05).CONCLUSION Rosiglitazone decreases blood glucose and improves insulin resistance, at the same time, it also lowers blood pressure in type 2 diabetes combined with hypertension.
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
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