Title: Effect of Fuzhisan on the viability of SH-SY5Y cell
Abstract:Objective To study the effect of Fuzhisan on the viability of ner ve cells. Methods Neuroblastoma cells (SH-SY5Y) were incubated with Fuzhisan in different concentrations. The survival rate of SH-SY5Y...Objective To study the effect of Fuzhisan on the viability of ner ve cells. Methods Neuroblastoma cells (SH-SY5Y) were incubated with Fuzhisan in different concentrations. The survival rate of SH-SY5Y cells was detected b y MTT assays. Concentration-effect Curve was made in order to select the optimal concentration of Fuzhisan. At first,a model of neuron injury in vitro was cul tured by incubating SH-SY5Y cells in Aβ25-35. Then,the model cells were incub a ted by Fuzhisan. In the end,MTT metabolizing rate,area of the cell's body and le ngth of its axon were investigated. Results Fuzhisan filled the roles of protecting SH-SY5Y cells fr om toxicity of Aβ25-35,increasing survival rate,guaranteeing and promoting gro wth of neurons. Conclusion Fuzhisan can indeed increase the viability of nerv e cells,and protect cells from Aβ25-35 toxicity.Read More
Publication Year: 2003
Publication Date: 2003-01-01
Language: en
Type: article
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Cited By Count: 1
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