Title: Expression of TGF-β1 in salivary gland mucoepidermoid carcinoma high and low metastatic cell lines
Abstract: Objective To investigate the expression of transforming growth factor beta 1(TGF-β1) in salivary gland mucoepidermoid carcinoma high and low metastatic cell lines.Methods TGF-β1 was examined by gene chip technique,RT-PCR,immunohistochemistry and Western blot in salivary gland mucoepidermoid carcinoma low metastatic cell line MEC-1 and high metastic cell line Ms.Results Stronger TGF-β1 expression was observed in Ms cells than in MEC-1 cells by gene chip technique and conformed by RT-PCR,immunohistochemistry and Western blot.Conclusion Over expression of TGF-β1 may contribute to the metastasis of salivary gland mucoepidermoid carcinoma.
Publication Year: 2006
Publication Date: 2006-01-01
Language: en
Type: article
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