Title: The Protective Effects of Shexiangbaoxin Dispersing Tablets in Dogs With Acute Myocardial Infarction
Abstract: Aim To investigate the protective effects of shexiangbaoxin dispersing tablets (SBDT) in dogs with acute myocardial infarction(AMI).Methods The acute myocardial model was established through ligatting left coronary artery anterior descending branch in the anaesthetized open-chest dogs.The parameters coronary blood flow,ECG,myocardial oxygen metabolish,myocardial infarct scope and the serum zymograms ect were determined in model dogs.Results In dogs treated with SBDT,the QT interphase was shorten and the elevation of ST was inhibited significantly in ECG.The cardiac oxygen consumption was decreased and the cardiac oxygen consumption index had downtrend.The activity of serum LDH,CK,CK MB,AST in 3 hours after ligation were decreased obviously.The myocardial infarct scope were decreased markedly.Conclusion SBDT possesses protective effects on acute myocardial ischemia.
Publication Year: 2003
Publication Date: 2003-01-01
Language: en
Type: article
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