Title: Effects of huoxue tongmai tablet on the level of myocardial ischemia and the extent of myocardial infarction in anesthetized canines
Abstract: AIM: To study the effects of HXTMT on the myocardial ischemia and myocardial infarction in experimental canines. METHODS: The coronary artery ligation was employed to establish the model of canines with acute myocardial ischemia and myocardial infarction. HXTMT was perfused into the duodenum. The extent of myocardial ischemia was detected by epicardialelectrocardiogram and the extent of infarction was determined by NBT staining method. RESULTS: It was indicated that the adminstration of HXTMT by way of gastrointestinal tract reduced the myocardial ischemia level (ST) (P0.05 P0.01) and the extent of myocardial infarction (NST). The results also showed that HXTMT reduced the infarction range marked by NBT staining method (P0.01). CONCLUSION: HXTMT can be used in the prevention and treatment of coronary heart disease.
Publication Year: 1999
Publication Date: 1999-01-01
Language: en
Type: article
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