Title: The Application Values of LAVA Enhanced MRI in Diagnosis of Cervical Cancer Lymph Node Metastasis
Abstract: Objective To assess the value of LAVA technique in diagnosis of lymph node involvement in cervical cancer.Methods We retrospectively recruited 36 patients with biopsy-confirmed cervical cancer in our hospital and evaluated the diagnostic performance of Gd-DTPA LAVA dynamic contrast enhanced MRI for pelvic lymph node involvement using surgicopathological findings as the reference standard.Results Seven hundred and fifty-nine lymph nodes were harvested from 288 lymph node regions;of these,33 lymph nodes from 21 lymph node regions were metastatic.MRI showed 42 lymph nodes in total,of which 28 lymph nodes showed heterogeneous enhancement patterns,and 2 showed central necrosis.When a short-axis diameter of more than 10 mm was applied as the criterion for the diagnosis of metastasis,the sensitivity and accuracy of MRI imaging in the diagnosis of lymph node metastasis on a region to region basis were 52.4% and 93.8%,respectively.The sensitivity and accuracy rates of heterogeneous enhancement patterns for detecting metastatic lymph nodes were 87.5%,61.9% respectively;for central necrosis,those rates were 12.5%,66.7%,respectively.Conclusion MRI enhanced imaging with LAVA scanned technique has a good predictive value in the diagnosis of lymph node metastasis in patients with cervical cancer.The short-axis diameter of more than 10 mm are useful in the evaluation of pelvic lymph node metastasis.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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