Title: Measurement of albuminuria and urinary β_2-microglobulin in patients with acute organophosphorus pesticide poisoning
Abstract: Objective:To evaluate the clinical significance of measuring albuminuria and urinary β2-microglobulin in patients with acute organophosphorus pesticide poisoning(AOPP).Methods:Radioimmunoassay technique was used to measure the albuminuria and urinary β2-microglobulin in 31 patients with AOPP and 34 healthy subjects were recruited as controls for comparing the results.Results: Of the 31 patients with AOPP,routine urine test on renal function was found positive in 12(38.7%).The level of albuminuria and urinary β2-microglobulin increased with progression of the poisoning,in particular,both levels were found higher than that of the controls on day 3 or 5 after intoxication(P 0.05).Still,the more severe cases suggested a marked higher level of albuminuria and urinary β2-microglobulin.Conclusion:The measurement of albuminuria and urinary β2-microglobulin is of great clinical significance in assessing early kidney injury with AOPP.
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
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