Title: Effect of somatostatin combined with prostaglandin E1 on severe acute pancreatitis
Abstract: Objective To study the clinical efficacy of somatostatin(SS) combined with prostaglandin E1(PGE1) in the treatment of severe acute pancreatitis.Methods Patients in control group were given the basic treatment(such as oxygen,fasting,gastrointestinal decompression,correcting water and electrolyte disturbance,acid-suppressing,anti-infective and nutritional support) and SS;patients in observation group were given PGEl on the basis of the treatment of control group.The clinical efficacy of the two groups was compared.Results The symptoms alleviating time,remission time of signs,resumed eating time and the average length of stay of observation group were significantly shorter than those of control group(P0.05);Blood amylase decreased more significantly in observation group after treatment for 3 d,5 d and 7 d,serum calcium rose more obviously after treatment for 2 d,3 d,5 d and 7 d,there were significant differences between the two groups(P0.05);The curative rate and total effective rate were 30.0% and 95.0% in observation group,while they were 10.5% and 78.9% in control group(P0.05).There was no significant difference in the adverse reactions between the two groups(P0.05).Conclusion SS combined with PGE1 in the treatment of severe acute pancreatitis is significantly better than single use of SS,it is worthy of clinical application.
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot