Title: Ovulation promoting effect of pioglitazone combined with chloramiphene on polycystic ovary syndrome
Abstract: Objective: To evaluate evaluation ovulation promoting effect of pioglitazone combined with chloramiphene on polycystic ovary syndrome(PCOS phenol).Methods: A total of 68 patients with PCOS patients were randomly divided into trial group and control group by half.Patients in trial group were treated by pioglitazone combined with chloramiphene,and patients in the control group by chloramiphene.Endometrium thickness,levels of serum estradiol(E2),corpus luteum erythropoietin(LH) and testosterone(T) were observed on the day when patients had injection of human chorionic gonadotropin(HCG),and pregnancy rate was also recorded.Results: Pregnancy rate of trial group was 24.52%,significantly higher than that in the control group(16.42%)(P0.05).Conclusion: Pioglitazone combined with chloramiphene can promote ovulation of PCOS patients,and increase pregnancy rate.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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