Title: Clinical Investigation on Treatment of Zhizhu Kuanzhong Capsule for Functional Dyspepsia
Abstract: Objective:To observe the clinical efficacy of Zhizhu Kuanzhong capsule in the treatment of functional dyspepsia(FD).Method: Eighty cases reached the standard of FD were randomly divided into treatment group,control group(n=40 each).Patients in two groups were orally given domperidone(10 mg,3 times daily),and asked to eat easy to digest food,to avoid other drugs with potential influences.The patients in treatment group were orally treated with Zhizhu Kuanzhong capsule(3 tablets,tid).Seven days were considered as a treatment course.After 3 courses of treatment,the outcome was compared for the two groups.Result: The cure rate was 75% in treatment group,and 62.50% in control group,with significant difference(P0.05).The total efficiency was 95% in treatment group,and 85% in control group,with significant difference(P0.05).The side effect scores of postoperative nausea and vomiting,loss of appetite,abdominal discomfort,belching,heartburn,acid reflux symptoms in treatmentt group were(0.94 ±0.27),(0.95±0.44),(0.75+0.37) points(0.25±0.45),(0.47±0.12),(0.76±0.22) accordingly,in the control group they were(1.76±0.32),(1.51±0.55),(1.75±0.52),(1.78±0.41),(1.45±0.54),(1.45±0.51) respectively.In two groups,the scores were decreased obviously after the treatment compared with those before the treatment(P0.05).The treatment group was better than the control group(P0.05).After treatment,normal slow wave before meals,normal slow wave after meals and the main power ratio before and after meals in the treatment group were(43.62±18.60)%,(52.32±1.54)%,(2.87±2.55),while in the control group(40.75±15.58)%,(46.32±16.64)%,(2.51±1.23) respectively.In two groups the treatments improved the parameters significantly(P0.05).The treatment group was better than the control group(P0.05).Conclusion: Clinical efficacy of Zhizhu Kuanzhong capsule for the treatment of FD is satisfactory.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot