Title: Clinical Observation of Empirical Triple Treatment for Chronic Functional Constipation with Combination of TCM and Western Medicine
Abstract:Objective:To observe the clinical efficacy and safety of empirical triple treatment for Chronic functional constipation with combination of TCM and Western medicine.Methods:180 patients were randomly ...Objective:To observe the clinical efficacy and safety of empirical triple treatment for Chronic functional constipation with combination of TCM and Western medicine.Methods:180 patients were randomly assigined to three groups according to 1:1:1 ratio.Administered the 60 cases of treatment group A with empirical treatment which were combined with TCM and Western medicine,administered the 60 cases of treatment group B with Forlax,administered the 60 cases of treatment group C with Mziren capsule and Forlax.The duration of treatment in groups was 1 month.Observed and scored symptoms of constipation before and at the end of the treatment,following up the cases one week later,four weeks later,and three months later.Evaluated and compared the effect by Nimodipine score.Results:At the end of the treatment,the effective rate were 91.38%(group A),86.67%(group B),94.73%(group C) respectively.Compared with group B and group C,group A has no significant difference(P0.05).followed-up 1 week after treatment,the effective rate were 87.93%(group A),73.33%(group B),77.19%(group C) respectively.Compared with group B and group C,group A has no significant difference(P0.05).Followed-up 1 month after treatment,the effective rate were 82.76%(group A),51.67%(group B),57.89%(group C) respectively.Compared with group B and group C,group A has no significant difference(P0.05).Followed-up 3 months after treatment,the effective rate were 65.52%(group A),23.33%(group B),33.33%(group C)respectively.Compared with group B and group C,group A has no significant difference(P0.05).The adverse reaction did not happen among three groups.Conclusion:Empirical triple treatment for chronic functional constipation with combination of TCM and Western medicine has the long-term efficacy and safety.Read More
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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