Title: The Application of Cystatin C(Cys C) in Valuation Acute Kidney Injury in ICU Patients
Abstract: Objective: To explore the application of Cystatin C(Cys C) in valuation acute kidney injury in ICU Patients.Methods: In this study,55 patients were collected and divided into two groups,including 31 cases with AKI and 24 cases without AKI as controls.We measured the serum concentration of Cys C,β 2-MG,and Cr by HITACHI 7600-120 Automatic biochemical analyzer.The eGFR was estimated the with MDRD equation.Then compared Cys C、Cr、β 2-MG between two groups and the correlations with each other.The diagnostic value of Cys C were evaluated by ROC curve with SPSS 16.0 software.Results: In AKI group,The serum level of Cys C were significantly higher than that in non-AKI group(P0.05),it has no significant difference among three periods(P0.05).-1 was also positively correlated with eGFR(r=0.711,P0.001).The ROCAUR of Cys C is 0.930.Conclusions: Cys C is a very useful diagnostic indicator in AKI,especially in the early diagnose AKI,it could provide a reliable assessment of renal function and grasp the right opportunity to better treatment.
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
Access and Citation
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot