Title: The angiopoietin-1/Tie2 system and the pathological angiogenesis
Abstract: Angiopoietin-1(Ang-1) is another important promoter in angiogenesis after the vascular endothelial growth factor(VEGF).The common specific receptor of angiopoietin family,including Ang-l,Ang-2,Ang-3 and Ang-4,is the Tie-2.It was proved that the Ang-1/Tie2 system was involved in the promotion of vascular maturation,inhibition of vascular leakage or inflammation,and played an important role in the process of pathological angiogenesis.
Publication Year: 2010
Publication Date: 2010-01-01
Language: en
Type: article
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