Title: Effect of Self- blood Acupoint Injection Therapy on the Th1 /Th2 Immune Deviation in Patients with Generalized Pruritus
Abstract: Objective: To observe the clinical effect of acupoint injection with self-blood therapy on generalized pruritus and the impact on serum levels of Th1 /Th2 cytokine. Methods: 66 patients with generalized pruritus were equally randomized into two groups. The patients in the treatment group( 33 cases) were treated by acupoint injection with self-blood therapy on the basis of oral loratadine,and those in the control group( 33cases) were given oral loratadine,and the treatment in two groups was for 4 weeks. Changes of symptoms and serum levels of Th1 cytokine: IFN-γ,IL-2 and Th2 cytokine: IL-4,IL-10 were observed before and after treatment. Results: The curative effect in the treatment group was better than that in the control group( P 0. 05). Levels of IFN-γ and IL-2 in the treatmeat group were significantly lower after treatment( P 0. 05),and they were lower than those in the control group( P 0. 05); Levels of IL-4 and IL-10 in the treatment group were significantly heightened after treatment( P 0. 05),and they were higher than those in the control group( P 0. 05). Conclusion: Acupoint injection with self-blood therapy shows a favorite effect on treating generalized pruritus and it may be achieved by regulating Th1 /Th2 cytokine levels to improve the immune status.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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