Title: Clinical outcomes of frozen-thawed embryo transfer cycles after pituitary suppression in patients with polycystic ovary syndrome
Abstract: Objective:To explore the influence of pituitary suppression on clinical outcomes of frozen-thawed embryo transfer cycles in patients with polycystic ovary syndrome(PCOS).Methods:A retrospective analysis was performed in 139 cycles which were failed by using hormone replacement and received treatments again.The cycles were randomly divided to two groups:hormone replacement group(group A,n=88)and hormone replacement combined with pituitary suppression group(group B,n=51).Results:No significant differences were found in patient's age,duration of infertility,the levels of basal sex hormones,body mass index,thickness of endometrium on progesterone conversion day,number of transferred embryos,quality embryo rate,post-thaw embryo survival rate,ectopic pregnancy,multiple pregnancy rate,and early miscarriage rate between the two groups.However,group A achieved significantly higher clinical pregnancy and implantation rate,and lower FSH,LH,E2 levels on hormone replacement treatment(HRT)day compared with group B.Conclusions:It is an effective and convenient method for frozen-thawed embryo transfer cycles with pituitary suppression in patients with polycystic ovary syndrome,It could obtain high pregnancy rate,embryo implantation rate and low cycle canceled rate.
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
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