Title: Three Cognitive Potentials of Depression and Anxiety Disorders:A Follow - up Study
Abstract: Objective To investigate the variations of contingent negative variations (CNV), P300 and mismatch negativity (MMN) in depression and anxiety disorders. Methods CNV,P300 and MMN were recorded from 44 depressive patients using Nicolet Spirit Instrument, and was compared with 32 anxiety patients and 28 normal controls ( NC ). Twenty - one depressive patients and 18 anxiety patients were followed up by 2.5 months with the same evoked potentials. Results 1. Compared with NC,all patients in acute episodes showed decreased Ml of CNV amplitude, delayed P3 latency, decreased P3 amplitude of P300, delayed MMN latency and decreased MMN amplitude ;2. The follow - up study of evoked potentials revaled that abnormal P3 of P300 and MMN latencies are significant between depressed patients in remission status and NC group but not P3 of P300 and MMN amplitudes; M1 of CNV, P3 of P300 amplitudes, P3 of P300 and MMN latencies were not significant between anxiety patients in remission and the NC group. Conclusion Delayed P3 of P300 and MMN latencies in depression show state and trait markers, while those variations in anxiety correlate with clinical status.
Publication Year: 2003
Publication Date: 2003-01-01
Language: en
Type: article
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