Title: Relationship of the expression of CD166 and MMP-9 to metastasis and prognosis of patients with non small cell lung cancer
Abstract: Objective To analyze the relationship of the expression of CD166 and MMP-9 to metastasis and prognosis of patients with non small cell lung cancer.Methods From January to December 2014,82 patients with NSCLC accepted radical operation of lung cancer resection.The expression of CD166 and MMP-9 was detected by immunohistochemical method.Results The expression of CD166 and MMP-9 showed clear difference in lymph node metastasis and different TNM staging( P 0.05).Spearman correlation analysis showed the expression of CD166 and MMP-9 was negatively correlated with lymph node metastasis in patients with lymph node metastasis.Conclusion The expression of MMP-9 and CD166 is high in patients with NSCLC,and lymph node metastases may be related with CD166 or MMP-9.The patients with the positive expression of MMP-9 and CD166 have poor prognosis.
Publication Year: 2015
Publication Date: 2015-01-01
Language: en
Type: article
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