Title: Clinical Study on the Protective Effect of Acupuncture of BL-15 and BL-14 Combined with Medication on Cardio-cerebral Functions in Patients with Acute Ischemic Stroke
Abstract: Objective:To study the protective effect of acupuncture combined with medication on cardiac and cerebral functions in patients suffering from acute ischemic stroke (AIS). Methods: 40 ischemic apoplectic patients were randomly divided into treatment group (n=20) which was treated by acupuncture of bilateral Xinshu (BL 15) and Jueyinshu (BL 14, once daily, ten sessions being a therapeutic course and 3 days' rest between two courses) combined with medication (20% mannitol, low molecular dextran, compound red sage root injection, persantine and aspirin) and control group (n=20) which was treated with simple medication (same medicines mentioned above). After 20 days' treatment, the therapeutic effect was evaluated. Changes of indices such as the volume of cerebral infarction, ECG-ST and T waves, heart rate (HR), plasma calcitonin gene-related peptide (CGRP), thromboxane B 2 (TXB 2) and 6-Keto-(prostaglandin) PGF1a contents, scores of neurological defect and clinical therapeutic effects were observed. Results: Following 2 courses of treatment, self-comparison of two groups showed that in comparison with pre-treatment, the cerebral infarction volume, HR and TXB 2 of treatment group were decreased significantly (P0.05~0.01),while no striking changes were found in cerebral infarction volume, HR, ECG-ST and T-wave amplitude, plasma CGRP, TXB 2, and 6-Keto- PGF1a contents of control group (P0.05). In addition, after treatment, the depressed ECG-ST and T-wave amplitudes of treatment group were elevated significantly compared with pre-treatment (P0.05). Plasma CGRP concentrations of two groups both increased significantly (P0.01~0.001), while the increased value of treatment group was evidently higher than that of control group (P0.01). Compared with pre-treatment, plasma TXB 2 and 6-Keto-PGF1a of treatment and control groups increased and decreased significantly and separately (P0.05). Following treatment, the scores for neurological defect of two groups both decreased significantly, while the decreased values of treatment group was significantly bigger than that of control group (P0.001). The total effective rate (70%) of treatment group was considerably higher than that (20%) of control group (P0.05). Conclusion: The protective effect of acupuncture plus medication on cardiac and cerebral functions in patients with ischemic stroke is significantly superior to that of simple medication.
Publication Year: 2003
Publication Date: 2003-01-01
Language: en
Type: article
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