Title: Laparoscopic radio-frequency ablation in the treatment of hepatocellular carcinoma or liver metastases
Abstract: Objective:To investigate the potential efficiency of radio frequency(RF) ablation of hepatocellular carcinoma or liver metastases.Methods:Under general anaesthesia,radio frequency electrodes were put into the liver for ablation to treat hepatocellular carcinoma or liver metastases.Results:Among the 32 hepatic cancer lesions in 10 patients,20(62.5%) lesions with diameter 5cm were ablated by one session.The effective rate (CR+PR) was 100%(20/20) with CR 75% (15/20) and PR 25%(5/20).During the 2 14 months follow up of these lesions,no recurrence was found by CT or MRI.12 lesions(37.5%) with 5cmΦ10cm were also ablated by one session,with CR 25%(3/12),PR 58.3%(7/12),MR 16.6%(2/12) and the effective rate(CR+PR) was 83.3%(10/12)by CT or MRI.Tumor markers such as AFP,CEA,CA19 9 were also become negative or fell down in 1 2 months after treatment.All patients tolerated the procedure well,no complications occurred after the ablation.One patient with the hepatocellular carcinoma died of disseminated disease at the 13 months. Conclusions:Laparoscopic radio frequency(RF) ablation in the treatment of hepatocellular carcinoma or liver metastases is effective on liver tumor with Φ≤5cm,and it's partly effective on lesions with 5cmΦ10cm.This procedure especially can be a safe,convenient and effective method to treat those patients of colorectal cancer with the liver metastases during the laparoscopic operations.
Publication Year: 2004
Publication Date: 2004-01-01
Language: en
Type: article
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