Title: EFFECT OF NERVE GROWTH FACTOR ON DIFFERENTIATION AND PROLIFERATION OF THE EMBRYONIC RAT SPINAL CORD NEURONS
Abstract: [Objective]To study the effect of nerve growth factor(NGF)on differentiation and proliferation of the embryonic rat spinal cord neurons.[Methods]After NGF was added to embryonic spinal cord neurons from the embryonic rat,the number of survival spinal cord neurons was counted and relative protein content in the cells was tested by light microscopy.[Results]The cultured embryonic spinal cord neurons body were aggrandized,the cell protuberance was prolonged,plenty of neuron fiber formed net work,the number of survival spinal cord neurons and the relative protein content increased,which showed the dose-effect relation.[Conclusion]Certain concentration of NGF(20.0~80.0 ng/ml)can promote the differentiation and proliferation of embryonic spinal cord neurons,and enhance the activity of the neurons.
Publication Year: 2007
Publication Date: 2007-01-01
Language: en
Type: article
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