Title: Synthesis and fungicidal activity of N-substituted 2-methyl-4-trifluoromethyl-5-thiazole carboxamides
Abstract:Seven novel 2-methyl-4-trifluoromethyl-thiazole-5-carboxamides were synthesized by reaction of 2-methyl-4-trifluoromethyl-5-thiazole chloride with aniline or amino pyridine derivatives.Their structure...Seven novel 2-methyl-4-trifluoromethyl-thiazole-5-carboxamides were synthesized by reaction of 2-methyl-4-trifluoromethyl-5-thiazole chloride with aniline or amino pyridine derivatives.Their structures were characterized by 1H NMR,IR,HRMS and elemental analysis.The preliminary bioassay showed that the inhibition rate of the title compounds were between 72.60%-91.78% against Pellicularia sasakii under 50 μg/mL,and the fungicidal activity of compound 6a was the highest.Read More
Publication Year: 2012
Publication Date: 2012-01-01
Language: en
Type: article
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