Title: Effects of flavone-hippophae on myocardial ischemia in aged patients with coronary artery disease
Abstract: Objective: To observe the effects of flavone-hippophae (sindacon) on myocardial ischemia in aged patients with coronary artery disease (CAD). Methods: Seventy-eight CAD cases were divided randomly into treatment group (40 cases) and control group (38 cases). The control group was treated with rout treatmentithe treatment group was treated with sindacon capsules 15mg, 3 times/d based on rout treatment. Both groups of patients were treated for consecutive 3 months. Results: In treatment group the average levels of TC, TG, LDL-C significantly decreased (P0. 01) and HDL-C increased (P0. 05) after treatment, and more than those of control group (P0. 01). The hemorheology indexes such as blood viscosity fibrionogen etc. markedly reduced (P0. 01 or P0. 05) after treatment in treatment group and more than those of control group (P0. 05). Myocardial ischemia significantly decreased in two groups (P0. 01 and P0. 05 respectively) after treatment, but it more decreased in treatment group than that in control group (P0. 05). No severe adverse effect was found in treatment group. Conclusion: Sindacon exerts significant effects on improving blood lipids, hemorheology, myocardial ischemia, it is an effective and safe drug for treatment of coronary artery disease.
Publication Year: 2005
Publication Date: 2005-01-01
Language: en
Type: article
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