Title: The change and significance of coagulative function index and platelet parameters in liver cirrhosis patients.
Abstract: Objective To explore the change and significance of coagulative function index and platelet parameters in liver cirrhosis patients.Methods The coagulafive function index(PT、 APTT、 TT and FIB) were detected with STAGO compact completely-automatic blond analyzer and platetet parameters(PLT、 MPV、 PDW and P-LCR) were detected with ABX PENTR120.Results Compared with control group,liver cirrhosis group had significantly higher levels of PT、 APTT、 TT(P0.05);lower levels of FIB(P0.05).Moreover,with the aggravation of liver cirrhosis,PT、APTT、 TT were gradually increased(P0.05) and FIB was gradually decreased(P0.05).Compared with control group,liver clrrhosis group had significantly higher levels of MPV、 PDW、 P-LCR(P0.05);lower levels of PLT(P0.05).Moreover,with the aggravation of liver cirrhosis,MPV、 PDW and P-LCR were gradually increased(P0.05) and PLT was gradually decreased(P0.05).Conclusion The coagulative function index and platelet parameters can help to determine the loss of liver function and the prognosis in liver cirrhosis.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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