Title: Treatment of 71 cases of Parkinson's disease by microelectrode-guided stereotactic pallidotomy and thalamotomy
Abstract: Objective To report the technique and result of treating Parkinson′s disease by microelectrode guided stereotactic pallidotomy and thalamotomy. Methods The localization of target was achieved by MRI and CT scans. Pallidal and thalamal target sites were supervised by microelectrode recording technique in 71 patients with Parkinson′s disease. Among all the patients, 12 cases of type A were undergone unilateral ventrolateral thalamotomy, 1 contemporary bilateral ventrolateral thalamotomy, 51 unilateral posteroventral pallidotomy, 1 contemporary bilateral posteroventral pallidotomy, 1 contemporary unilateral ventrolateral thalamotomy and posteroventral pallidotomy and 5 postponed bilateral posteroventral pallidotomy. Evaluation of UPDRS motor score was made, before and 12 months after the operation. Results Within 12 months after the operation , tremor was resolved completely or nearly completely in 12 patients who had been underwent unilateral and 1 bilateral ventrolateral thalamotomy, and mandible tremor had been improved in 2 patients. Tremor, rigidity, bradykinesia were dramitically improved in 58 patients underwent posteroventral pallidotomy, among them, 6 had been undergone bilateral posteroventral pallidotomy. Intracerebral hemorrhage was observed in 1 patient. Conclusion Microelectrode guided stereotactic pallidotomy and thalamotomy are effective measures for the treatment of Parkinson′s disease, but probably may bring about serious complications.
Publication Year: 2001
Publication Date: 2001-01-01
Language: en
Type: article
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