Title: Non-small-cell lung cancer in elderly patients:surgical treatment of 263 cases
Abstract: Objective To study the prognosis of non-small-cell lung cancer(NSCLC) in elderly patients after surgery. Methods The record of of 263 survival elderly patients with NSCLC who underwent surgery from 1999 to 2004 was statistically analyzed by the Kaplan-Meier method. Comparison of the differences in survival rates among groups was made according to the log rank test. The follow-up time was at least 5 years with a follow-up rate of 92.5%. Results Of 263 cases,35(13.3 %) patients were in the stage Ⅰ of cancer,92(35.0%) in stage Ⅱ,136(51.27%) in stage Ⅲ. Surgical procedures included segmentectomy and wedge resection for 22 patients(8.4% ),lobectomy for 197 cases (72.6%),bilobectomy for 16 cases (6.1% ),sleeve lobectomy for 19 patients(7.2%),and pneumonectomy for 9 patients(3.4% ). The overall 1-,3-,5-year survival rates for elderly patients with pathologic stage lesion were 69.2%,41.2% and 28.7%. The 5-year survival rates for stageⅠ,Ⅱ,Ⅲ were 66.5%,38.3% and 16.2%. respectively (P0.05).Fifty-eight cases(22.0%) had severe complications and early operative mortality was 1.9% after lung cancer surgery. Conclusion Elderly patients with non-small-cell lung cancer should undergo surgical therapy. Operative indications and careful perioperative management are necessary for obtaining good therapeutic results and long-term prognosis in elderly patients.
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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