Title: Surgical treatment of 116 elderly patients with non small cell lung cancer
Abstract: Objective To study the prognosis of non small cell lung cancer(NSCLC) in elderly patients after surgery.Methods 116 NSCLC patients of 70 year or older underwent surgery treatment from 2005 to 2008.The data were statistically analyzed by Kaplan-Meier method.Comparison of the differences in survival rates among groups was made according to the Log-Rank test.The follow-up time was more than 5 years and follow-up rate was 91.4%.Results Of 116 cases,17(14.7%) patients were in stageⅠ,42(36.2%) were in stageⅡ,57(49.1%) were in stageⅢ.Surgery procedure include pneumonectomy for 9 patients(7.8%),lobectomy for 97 patients(83.6%),segementectomy and wedge resection for 10 patients(8.4%).The five year survival rate for stage Ⅰ,Ⅱ,Ⅲ were 65.3%,42.6%,18.7%,respectively(P 0.05).The DFS of postoperative patients with Ⅰ,Ⅱ,Ⅲ were(61.7 ± 3.5) months,(44.8 ± 3.7) month,(28.9 ± 2.6) month(F = 8.741,P = 0.005).The OS of postoperative patients withⅠ,Ⅱ,Ⅲwere(66.3 ± 2.7) months,(54.6 ± 1.8) months,(32.7 ± 2.4) months(F = 4.941,P = 0.036).47 patients(40.5%) had severe complications.The perioperative mortality was 1.7%.Conclusion Elderly patients with NSCLC should undergo surgical therapy.Preoperative period combined lung or cardiovascular disease is not surgery contraindications.Operative indications and proper pattern of surgery were necessary for doctors to obtain good therapeutic results and long-term prognosis in elderly patients.
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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