Title: Effect of lactulose in treating endotoxemia in patients with hepatic cirrhosis due to hepatitis B
Abstract: Objective To observe the clinical efficacy of lactulose in treaing endotoxemia in patients with hepatic cirrhosis due to hepatitis B. Methods Seventy patients with hepatic cirrhosis due to hepatitis B were randomly divided into the treated group ( n = 35 ) and the control group ( n = 35 ) . Patients in the control group received conventional treatments for 20 days. Besides conventional treatments, patients in the treated group received lactulose for 20 days. Results In the treated group, the improvement rate of endotoxemia was 85. 7% ,significandy better than the control group 45. 6% (x~2 = 10. 94, P 0. 01). Serum endotoxin, ALT、AST and TBIL were all lower in the treated group than those in the control group (P 0. 05 or P 0. 01) . Conclusion Lacunose can decrease the level of serum endotoxin. Lactulose is significant effective in the treatment of endotoxemia in patients with hepatic cirrhosis due to hepatitis B, and better than the control group.
Publication Year: 2011
Publication Date: 2011-01-01
Language: en
Type: article
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