Title: Diltiazem Combined with Nifedipine in Treatment of Twenty Patients with Kidney-Transplanted Hypertension
Abstract:Objective:To study the therapeutic effect of diltiazem with nifedipine after kidney-transplantation with ciclosporin(CsA). Methods:Fourty patients were randomly divided into 2 group evenly. The treatm...Objective:To study the therapeutic effect of diltiazem with nifedipine after kidney-transplantation with ciclosporin(CsA). Methods:Fourty patients were randomly divided into 2 group evenly. The treatment group took diltiazem 30 mg, po, bid, and nifedipine 10mg, po, tid. The control group received nifedipine 10 mg, po, tid. The drug dosages were adjusted according to the level of blood pressure. The artery pressure and renal function were checked for more than 2 years. Results:Diltiazem changed the metabolism of CsA, resulting in a forty percent reduction in CsA dose. But the risk of CsA toxicity did not increase. Conclusion:Diltiazem with nifedipine can safely be used in the treatment of hypertension after kidney transplantation, and can lower the dose of CsA.Read More
Publication Year: 2004
Publication Date: 2004-01-01
Language: en
Type: article
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