Title: Advances in Study of Biosynthesis of Artemisinin
Abstract:Artemisinin,an endoperoxide sesquiterpene lactone isolated from Artemisia annua L.,is an effective drug against multidrug resistant strains of malarial parasite,Plasmodium.In this paper,the biosynthes...Artemisinin,an endoperoxide sesquiterpene lactone isolated from Artemisia annua L.,is an effective drug against multidrug resistant strains of malarial parasite,Plasmodium.In this paper,the biosynthesis pathway for artemisinin was proposed on the basis of the transformation of some precursor such as arteannuin B and artemisinic acid. The function and constituents of the key enzymes involved in the biosynthesis were discussed to reveal the synthetic path. The genetic manipulation on artemisinin biosynthesis was also introduced for the possibility on artemisinin production by biotechniques.Read More
Publication Year: 2009
Publication Date: 2009-01-01
Language: en
Type: article
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