Title: A comparison of sufentanil, fentanyl or tramadol in combination with ropivacaine for postoperative caudal analgesia in children
Abstract: Objective To compare the efficacy and safety of caudal analgesia with 0.5% ropivacaine plus 0.8 μg/kg sufentanil, 3 μg/ml fentanyl, or plus 1 mg/kg tramadol,in children for postoperative analgesia.Methods Eighty ASA class Ⅰ children,between 1 to 6 years old, scheduled for elective inferior belly surgery under ketamine basal anaesthesia and midazolam sedation were recruited. The patients were randomly divided into four groups with 20 cases each of receiving caudal ropivacaine alone (0.5%) in group A, ropivacaine(0.5%) plus sufentanil (0.8 μg/ml) in group B, ropivacaine (0.5%) plus fentanyl(3 μg/ml) in group C or ropivacaine (0.5%) plus tramadol(1 mg/ml) in group D. The volume (ml) = [the distance (cm) between the processus spinsus of 7th cervical vertebra and upper edge of hiatus sacralis-15 ]/2+4. Intraoperative administered ketamine10-20 mg via i.v. were recorded. When the patients were fully awake in the recovery area, heart rate, arterial pressure, peripheral oxygen saturation, respiratory rate, pain were recorded at 2, 4, 6, 8, 12 and 24 h postoperatively and side-effects were noted. Pain was assessed using an objective pain score (OPS).Results No patient experienced hypotension or respiratory depression. The efficacy and duration of analgesia in group B,C and D were significantly better than that in group A at 4,6 h during postoperative analgesia(P0.05).The analgesic effect of group B and D was significantly better than that of group A and C at 8,12,24 h during analgesia.The incidence of nausea and vomiting was higher in group B than that in the other groups.Conclusion Sufentanil combined with ropivacaine is effective and safe for postoperative caudal analgesia in children.
Publication Year: 2007
Publication Date: 2007-01-01
Language: en
Type: article
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