Title: Study of quality standard for Chaiqin Soft Capsule
Abstract: Objective To establish the quality standards of the new medicine Chaiqin Soft Capsule.Methods Radix bupleuri,radix puerariae,sophora tonkinensis and rhizoma cimicifugae were identified by TLC;and the content of baicalin in scutellaria baicalensis was determined by HPLC.The HPLC system was with Diamonsil C18(250 mm×4.6 mm;5 μm) column,the mobile phase was methanol-water-phosphoric acid(47 ∶53∶0.2),flowing rate was 1.0 mL/min,UV detecting wavelength was at 280 nm and the column temperature were at 20 ℃.Results The test product,the reference drug and the reference standard chromatographic had the same color of the spots in the corresponding position but the negative sample excepted.The study on the quality control showed that the characteristic of identification by TLC was distinct and highly specific,Baicalin showed a good linear relationship at a range of 0.28-1.40 μg(r = 0.9999),the average recovery was 99.74%,RSD was 0.85%.Conclusion The method can effectively control the quality of products.
Publication Year: 2013
Publication Date: 2013-01-01
Language: en
Type: article
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