Title: Early Detection of Carotid Decreased Elasticity by Echo-Tracking Technology in Essential Hypertension Patients
Abstract: Objective To evaluate E-Tracking technology in detecting early elasticity changes in the carotid ar- tery in essential hypertension(EH)patients.Methods Eighty-two cases of EH patients were categorized accord- ing to the finding of B-mode ultrasonography of carotid artery:abnormal carotid group(n=43)with intima-media thickning and/or with plaques in one or both sides;normal carotid group(n=39);normal healthy subjects(n=50) were selected as controls.Echo-Tracking(E-T)technology was performed to follow the movement tracks of the common carotid arterial wall.Systolic diameter of common carotid artery(Ds),diastolic diameter of common carot- id artery(Dd),pressure-strain elastic modulus(E_ρ),stiffness parameter(β),arterial compliance(AC),pulse wave conducting velocity(PWVβ)and augment index(AI)were determined by echo-tracking examination.Results The parameters showing in decreased elasticity of artery,Ep(abnormal carotid:219.2±60.5,normal carotid:140.6± 51.5 vs control:90.5±23.9,P0.01),β(abnormal carotid:16.1±7.8,normal carotid:13.1±4.0 vs control: 8.3±3.0,P0.01),PWVβ(abnormal carotid:8.38±1.13,normal carotid:7.14±0.92 vs control:5.94±0.65, P0.05),AI(abnormal carotid:19.07±9.97,normal carotid:18.86±6.83 vs control:12.45±4.59,P0.01) were all increased,while dimension of carotid artery,as Ds(abnormal carotid:7.94±1.35,normal carotid:8.02± 1.28 vs control:7.50±1.20,P0.05)and Dd(abnormal carotid:7.63±1.19,normal carotid:7.60±1.22 vs control:7.01±1.01,P0.05)were increased concomitantly associated with lower AC(abnormal carotid:0.70± 0.17,normal carotid:0.74±0.26 vs control:0.88±0.22,P0.05).Conclusion The elasticity of the carotid artery in EH was changed before the occurrence of intima-media thickning or plaques.The Echo-Tracking technol- ogy can be used to detect the early elasticity changes of arteriosclerosis.
Publication Year: 2008
Publication Date: 2008-01-01
Language: en
Type: article
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