Title: Study on diffusion-weighted imaging in the diagnosis of hyperacute cerebral infarction
Abstract: Objective In this study we compared the sensitivity of DWI with that of conventional MRI techniques,so as to evaluate the diagnostic accuracy of diffusion weighted magnetic resonance(MR) imaging performed within 6 hours of the onset of stroke symptoms. Methods We performed DWI,fluid attenuated inversion recovery,fast spin echo T 2 weighted MRI,3D TOF MRA in 52 patients with hyperacute,acute,subacute,chronic stroke. In all cases,the neuroanatomic locations of the lesions were precisely determined,and an experienced neurologist judged if the location of the lesion seen on MRI was in agreement with the patient's symptoms and signs. Results Hyperacute and acute infarcts appeared as areas of hyperintensity on DW images and hypointensity on ADC map,the ADC value was less than that of contralateral corresponding region. In hyperacute and acute stage,ADC decreased and rADC decreased by 59.12%;in contrast,it increased by 20.3% in chronic stage. Conclusion Diffusion weighted MR imaging is highly accurate for diagnosing stroke within 6 hours of symptom onset and is superior to conventional MR imaging. DWI could demonstrate ischemic area at early stage,much earlier than T 2WI and FLAIR. DWI plays an important role in making early diagnosis and evaluation of cerebral infarction.
Publication Year: 2003
Publication Date: 2003-01-01
Language: en
Type: article
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