Title: Tea-pigment vs gemfibrozil in treating hyperlipidemia and high uric acid in blood
Abstract: AIM: To compare the effect and safety of tea-pigment and gemfibrozil in treating hyperlipidemia and complication of high uric acid. METHODS: Eighty patients (M 54, F 26; age 65 ± s 6 a) received tea-pigment 125 mg, po, tid for 60 d, and 45 patients(M 29, F 16, ape 64 ± 5 a) received gemfibrozil 300 mg, po, tid for 60 d. RESULTS: The total effective rates for reducing cholesterol (TC) and triglyceride (TG) in tea-pigment group and gemfibrozil group were 82%, 84% and 63 %, 81 % respectively(P 0. 05 ). The total effective rates for raising high density lipoprotein cholesterol (HDL-C) in tea-pigment group and gemfihrozil group were 74 %, 65 % respectively (P 0. 05 ). The serum uric acid was reduced significantly in 41 patients with both hyperlipidemia and high uric acid treated by tea-pigment. No remarkable adverse reaction was found in tea-pigment group, while transient elevation of serum ALT was observed in 19 patients (42% ) in gembibrozil group. CONCLUSION: Tea-pigment is a good drug in adjusting serum lipid and reducing serum uric acid tea-pigment in adjusting serum lipid effect is equal to gemfibrozil.
Publication Year: 2000
Publication Date: 2000-01-01
Language: en
Type: article
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